HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65

System innovation experimentation for Industry 5.0 (IA) -

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Call text (as on F&T portal)

View on F&T portal
Expected Outcome:

Proposals are expected to contribute to the following outcomes:

  • Demonstrated successful incentives for systemic transformation towards Industry 5.0[1] and for skills upgrading and boosting the competitiveness of EU industries.
  • Development and application of Industry 5.0 enabling conditions, processes and methods for systemic transformation, organisational learning capacities and revitalisation of industries at regional/local level.
  • Demonstrate / provide evidence on the implementation of Industry 5.0 innovations for better adaptation of industries to new challenges linked to twin transition (enhanced resilience), organisational agility, and contribute to tackling the skills gap / attraction of best talent in regional industrial ecosystems
Scope:

Industry 5.0 is a framework grounded in system thinking approach which aims to bolster the economic and environmental resilience of industrial ecosystems and companies and contribute to enhancing the sustainable competitiveness of EU industries.[2] Industry 5.0 innovations such as human-centric technologies or learning organisation models contribute to tackling the new emerging challenges linked to ongoing green and digital transition such as addressing the skills gap, attracting the best talent or accelerating uptake of clean technologies.[3]

Proposals should elaborate on an Industry 5.0-driven methodology framework via system innovation experimentation in different industrial ecosystems in European Regional Innovation Valleys and other regions, to support deployment of Industry 5.0 innovations or methods at regional / local industrial ecosystems level:

a) offer innovative approaches to accelerate industrial transformation at regional/local level while tackling the new emerging challenges such as skills gap or attracting the best talent.

b) experiment to develop incentives towards longer-term industry 5.0 transformation.

The project should build on the results of the “Community of Practice on Industry 5.0”[4] and other Horizon Europe Industry 5.0 (or related) funded projects. Proposals should involve appropriate expertise in Social Sciences and Humanities (SSH), in particular in systems thinking or complexity science and their practical implementation as part of system innovation or transformation initiatives.

The proposal should include details on processes to identify a concrete long-term transformative innovation challenge for the industrial ecosystems or actors participating, to formulate concrete objectives addressing systemic issues related to how the industrial ecosystem could boost its future competitiveness, and achieve Industry 5.0 goals, and in particular focused on attracting skilled employees, creating the conditions for learning ecosystems or learning organisations. The challenge should guide the next steps on industrial transformation processes and experimentation.

For each of the identified transformation challenge, the project should engage stakeholders in transdisciplinary research and innovation activities, including in:

a) Identifying and testing new Industry 5.0 driven methods and measures for organisational transformation, learning organisation implementation and system innovation, to support the scaling up of Industry 5.0 and skills for competitive and future-oriented industry transformation:

  • Identifying the package of systemic innovations available to reach the set goals, including advanced technologies designed with responsible practices (human-centric, ecological, bio-inspired, biomimicry, nature-based solutions etc.), business models, new work processes, organisational models, governance or social innovations that can support Industry 5.0 transformation.
  • Assessing skills needs and learning areas for the workforce and organisations in the industrial innovation ecosystem, in view of the identified systemic innovations.
  • Identifying the incentives, leverage points and / or behavioural aspects that would support the organisations’ evolution to industry 5.0, building on existing results of Industry 5.0 funded projects and connected initiatives.
  • Identifying successful methodologies to develop systemic innovation incentives to promote Industry 5.0 paradigm change, human-centric enabling technologies, learning organisation model adoption and skills upgrade for Industry 5.0 goals.

b) Developing and testing the new methodologies through sandboxes, open innovation approaches or participatory processes for systemic transformation by prototyping new incentives schemes or enabling measures. The sandboxes should involve quadruple or quintuple helix stakeholders at regional/local level to support the achievement of the identified transformational challenge and contribute to acceleration of place-based industrial transformation:

c) Develop tools/measures to build evidence on and promote the impact of Industry 5.0 methods for industrial transformation at regional/local level, such as:

  • Digital or AI-enabled tools to support rapid conversion and orchestration of information that can support decision-making and anticipation of the pipelines of innovations, value chain evolution, skills needs or transformation opportunities.
  • Peer learning across the supported ecosystems, focused on the improvement of organisational learning capacity, learning ecosystems development and new innovation capacity for Industry 5.0 transformation, inspired by new paradigms in organisational design, learning and innovation. This should also include actions catalysing leadership for Industry 5.0 paradigm change. Document the results to inform and advise policy-makers in view of their potential upscaling.

Proposals submitted under this topic should include an exploitation strategy.

The project should build on or seek collaboration with existing projects developing Industry 5.0 solutions and/complementary to Industry 5.0 pillars and methods such as Regional Innovation Valleys or New European Bauhaus. It should also develop synergies and ensure complementarities with other relevant European, national or regional initiatives, funding programmes and platforms, such as Digital Innovation Hubs, European Partnerships like Made in Europe, Process4Planet, AI, Data and Robotics Partnership and the relevant EIT KICs.

The Commission considers that proposals in this topic with an overall duration of typically 36 months would allow these outcomes to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other durations.

[1] Industry 5.0 - European Commission (europa.eu)

[2] European Commission, Directorate-General for Research and Innovation, Renda, A., Schwaag Serger, S., Tataj, D. et al., Industry 5.0, a transformative vision for Europe – Governing systemic transformations towards a sustainable industry, Publications Office of the European Union, 2021, https://data.europa.eu/doi/10.2777/17322

[3] European Commission: Directorate-General for Research and Innovation, ERA industrial technologies roadmap on human-centric research and innovation for the manufacturing sector, Publications Office of the European Union, 2024, https://data.europa.eu/doi/10.2777/0266

[4] Industry 5.0 Community of Practice | Futurium

News flashes

2025-12-06

CALL UPDATE: PROPOSAL NUMBERS

Call HORIZON-CL4-2025-01 has closed on the 23/09/2025.

639 proposals have been submitted.

The breakdown per topic is:

Topic ID

Topic title

Action type

Proposals submitted

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01

Integrated approaches for remanufacturing (Made in Europe Partnership) (IA)

IA

80

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02

Physical and cognitive augmentation in advanced manufacturing (Made in Europe Partnership) (RIA)

RIA

94

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05

Advanced manufacturing technologies for leadership of EU manufacturers in products for the net-zero industry (Made in Europe Partnership) (IA)

IA

64

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31

From heat-driven processes to the use of mechanical and electric forces (Processes4Planet Partnership) (IA)

IA

13

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32

Green and resilient flexible production processes (Processes4Planet Partnership) (IA)

IA

19

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33

Integrated use of renewable energy carriers in industrial sites (Processes4Planet Partnership) (RIA)

RIA

35

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34

Smart integration of net zero technologies into Energy Intensive industries (Processes4Planet and Made in Europe Partnerships) (IA)

IA

12

TWIN-TRANSITION-36

Safe and clean processing technologies and products (Processes4Planet Partnership) (RIA)

RIA

25

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37

Solving issues in carbon-neutral iron and steel making processes with diverse input materials of varying quality (Clean Steel Partnership) (RIA)

RIA

22

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38

Synergies and mutual learning with national and regional initiatives in Europe on Industrial decarbonisation (Processes4Planet and Clean Steel Partnerships) (CSA)

CSA

1

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39

Towards human-centric, sustainable and resilient energy-intensive industries (Processes4Planet and Clean Steel Partnerships) (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31

Digitally enabled local-for-local textile and apparel production (Textiles for the Future Partnership) (IA)

IA

33

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44

Innovative Advanced Materials Innovation Procurement (CSA)

CSA

4

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45

Materials Commons for Europe (IA)

IA

3

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52

Accelerate the uptake of life-cycle assessment (LCA) for Safe and Sustainable by Design (SSbD) chemicals and materials and resulting products (RIA)

RIA

35

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61

Technologies for critical raw materials and strategic raw materials from end-of-life products (IA)

IA

38

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62

Strategic Partnerships for Raw Materials: Innovative approaches for sustainable production of Critical Raw Materials (IA)

IA

31

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63

Innovative solutions for the sustainable production for semiconductor raw materials (IA)

IA

7

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64

EU Co-funded Partnership on raw materials for the green and digital transition (Programme Co-fund action)

COFUND

1

HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61

AI Foundation models in science (GenAI4EU) (RIA)

RIA

47

HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62

Facilitated cooperation for AI in Science (CSA)

CSA

7

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60

Horizon Standardisation Booster (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61

Standardisation landscape analyses tool (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62

Artificial Intelligence for knowledge valorisation (CSA)

CSA

15

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63

Value creation pilots for scaling up innovative solutions (CSA)

CSA

10

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64

Pilot initiatives on Technology Infrastructures (CSA)

CSA

20

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65

Network of Industry 5.0 system innovation hubs in connected Regional Innovation Valleys (IA)

IA

8

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66

Assessment of Technology Infrastructure needs in Ukraine (CSA)

CSA

6

Total:

639

Evaluation results are expected to be communicated around mid-January 2026.

A.R.

2025-12-06

Reminder on proposal part B page limit and formatting conditions

1.    Proposal part B page limit

The title, list of participants and sections 1, 2 and 3, together, should not be longer than page limit, indicated in a proposal part B template inside the Submission System. All tables, figures, references and any other element pertaining to these sections must be included as an integral part of these sections and are thus counted against this page limit.

The page limit will be applied automatically. At the end of a proposal part B template inside the Submission System you can see the structure of the actual proposal that you need to submit, please remove all instruction pages that are watermarked.

If you attempt to upload a proposal longer than the specified limit before the deadline, you will receive an automatic warning and will be advised to shorten and re-upload the proposal. After the deadline, excess pages (in over-long proposals/applications) will be automatically made invisible, and will not be taken into consideration by the experts. The proposal is a self-contained document. Experts will be instructed to ignore hyperlinks to information that is specifically designed to expand the proposal, thus circumventing the page limit.

Please, do not consider the page limit as a target! It is in your interest to keep your text as concise as possible, since experts rarely view unnecessarily long proposals in a positive light.

2.Proposal part B formatting conditions

The following formatting conditions apply (as listed in a proposal part B template inside the Submission System) and will be checked by the Agency during an admissibility check of submitted proposals.

The reference font for the body text of proposals is Times New Roman (Windows platforms), Times/Times New Roman (Apple platforms) or Nimbus Roman No. 9 L (Linux distributions).

The use of a different font for the body text is not advised and is subject to the cumulative conditions that the font is legible and that its use does not significantly shorten the representation of the proposal in number of pages compared to using the reference font (for example with a view to bypass the page limit).

The minimum font size allowed is 11 points. Standard character spacing and a minimum of single line spacing is to be used. This applies to the body text, including text in tables.

Text elements other than the body text, such as headers, foot/end notes, captions, formula's, may deviate, but must be legible.

The page size is A4, and all margins (top, bottom, left, right) should be at least 15 mm (not including any footers or headers).

Proposal part B template inside the Submission System document is tagged. Do not delete the tags; they are needed for our internal processing of information, mostly for statistical gathering. In that light, please do not move, delete, re-order, alter tags in any way, as they might create problems in our internal processing tools. Tags do not affect or influence the outcome of your application.

2025-12-06

Please note that due to a technical issue, during the first days of publication of this call, the topic page did not display the description of the corresponding destination. This problem is now solved. In addition to the information published in the topic page, you can always find a full description of destinations:

* destination 1: Achieving global leadership in climate-neutral, circular and digitised industrial and digital value chains;

* destination 2: Achieving technological leadership for Europe's open strategic autonomy in raw materials, chemicals and innovative materials;

* destination 4: Achieving open strategic autonomy in digital and emerging enabling technologies;

* destination 6: Digital and industrial technologies driving human-centric innovation,

that are relevant for the call in the Work Programme 2025 part for “Industry”. Please select from the work programme the destination relevant to your topic and take into account the description and expected impacts of that destination for the preparation of your proposal.

2025-12-06
The submission session is now available for: HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66, HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-36, HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62
call topic details
Call status: Closed
Publication date: 2025-05-22 (6 months ago)
Opening date: 2025-05-22 (6 months ago)
Closing date: 2025-09-23 (2 months ago)
Procedure: single-stage

Budget: 3,000,000
Expected grants: 1
Contribution: 3,000,000 - 3,000,000
News flashes

This call topic has been appended 4 times by the EC with news.

  • 2025-12-06
    call update: proposal numberscall horizo...
  • 2025-12-06
    reminder on proposal part b page limit a...
  • 2025-12-06
    please note that due to a technical issu...
  • 2025-12-06
    the submission session is now available...
Source information

Showing the latest information. Found 9 versions of this call topic in the F&T portal.

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  • 2025-10-28_15-46-22
  • 2025-07-02_03-31-07
  • 2025-07-01_03-30-45
  • 2025-06-27_03-30-46
  • 2025-06-21_03-30-34
  • 2025-06-16_03-30-36
  • 2025-06-11_03-30-16
  • 2025-05-22_03-30-14
  • 2025-05-15_03-30-19

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Events

This is just a very first implementation, better visualisation coming

Horizon Europe info days - Cluster 4

2025-05-13 -> 2025-05-14

online

This event aims to inform potential applicants about the funding opportunities within the Work Programme 2025 of the Horizon Europe Cluster 4 'Digital, Industry and Space'.

Horizon Europe - Industry 2025 Brokerage event

2025-05-14 -> 2025-09-23

online

NCP4Industry, the network of Cluster 4 - Industry National Contact Points and the Enterprise Europe Network are organising a brokerage event with pre-arranged online Face2Face meetings complementing the European Commission's Horizon Europe Information Day on Cluster 4 - Digital, Industry & Space with a 2025 deadline.

Events are added by the ideal-ist NCP community and are hand-picked. If you would like to suggest an event, please contact idealist@ffg.at.

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    - 8 months ago

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  2. Publication date

    - 6 months ago

    The call was published on the Funding & Tenders Portal.

  3. Opening date

    - 6 months ago

    The call opened for submissions.

  4. Closing date

    - 2 months ago

    Deadline for submitting a project.

  5. Today

  6. Time to inform applicants Estimate

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    The maximum time to inform applicants (TTI) of the outcome of the evaluation is five months from the call closure date.

  7. Sign grant agreement Estimate

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    The maximum time to sign grant agreements (TTG) is three months from the date of informing applicants.

Funded Projects

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Project information comes from CORDIS (for Horizon 2020 and Horizon Europe) and will be sourced from F&T Portal (for Digital Europe projects)

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